ID   WiT49
AC   CVCL_0583
SY   WiT 49
DR   MCCL; MCC:0000489
DR   cancercelllines; CVCL_0583
DR   Cosmic; 1196557
DR   IARC_TP53; 18935
DR   Wikidata; Q54994118
RX   PubMed=8623926;
RX   PubMed=14506735;
RX   PubMed=19824073;
WW   https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/w/cell-lines-detail-622.html
CC   Characteristics: Established from a first-generation nude mouse subcutaneous xenograft.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (PubMed=14506735).
CC   Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
DI   NCIt; C40407; Kidney Wilms tumor
DI   ORDO; Orphanet_654; Nephroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   24Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 17
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RX   PubMed=8623926; PMCID=PMC1861544;
RA   Lahoti C., Thorner P.S., Malkin D., Yeger H.;
RT   "Immunohistochemical detection of p53 in Wilms' tumors correlates with
RT   unfavorable outcome.";
RL   Am. J. Pathol. 148:1577-1589(1996).
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RX   PubMed=14506735; DOI=10.1002/ijc.11429;
RA   Alami J., Williams B.R.G., Yeger H.;
RT   "Derivation and characterization of a Wilms' tumour cell line, WiT
RT   49.";
RL   Int. J. Cancer 107:365-374(2003).
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RX   PubMed=19824073; DOI=10.1002/pbc.22205; PMCID=PMC2834252;
RA   Li M.-H., Yamase H., Ferrer F.;
RT   "Characterization of a WiT49 cell line derived orthotopic model of
RT   Wilms tumor.";
RL   Pediatr. Blood Cancer 54:316-318(2010).
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