ID   U-1752
AC   CVCL_0565
SY   U1752; 1752
DR   BTO; BTO_0005386
DR   MCCL; MCC:0000467
DR   cancercelllines; CVCL_0565
DR   Cosmic; 953988
DR   Cosmic; 1006541
DR   IARC_TP53; 18700
DR   Wikidata; Q54973517
RX   PubMed=2983887;
RX   PubMed=2990154;
RX   PubMed=6178358;
RX   PubMed=6272398;
RX   PubMed=9551745;
RX   PubMed=12820372;
RX   PubMed=21508355;
CC   Doubling time: 36 hours (PubMed=6178358).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ala347Thr (c.1039G>A); ClinVar=VCV000662690; Zygosity=Unspecified (PubMed=12820372).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C3493; Lung squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   39Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 17
//
RX   PubMed=2983887;
RA   Saksela K.M., Bergh J., Lehto V.-P., Nilsson K., Alitalo K.;
RT   "Amplification of the c-myc oncogene in a subpopulation of human small
RT   cell lung cancer.";
RL   Cancer Res. 45:1823-1827(1985).
//
RX   PubMed=2990154; DOI=10.1111/j.1699-0463.1985.tb03932.x;
RA   Bergh J., Nilsson K., Ekman R., Giovanella B.C.;
RT   "Establishment and characterization of cell lines from human small
RT   cell and large cell carcinomas of the lung.";
RL   Acta Pathol. Microbiol. Immunol. Scand. A. 93:133-147(1985).
//
RX   PubMed=6178358;
RA   Bergh J., Nilsson K., Zech L., Giovanella B.C.;
RT   "Establishment and characterization of a continuous lung squamous cell
RT   carcinoma cell line (U-1752).";
RL   Anticancer Res. 1:317-322(1981).
//
RX   PubMed=6272398; DOI=10.1126/science.6272398;
RA   Moody T.W., Pert C.B., Gazdar A.F., Carney D.N., Minna J.D.;
RT   "High levels of intracellular bombesin characterize human small-cell
RT   lung carcinoma.";
RL   Science 214:1246-1248(1981).
//
RX   PubMed=9551745; DOI=10.1183/09031936.98.11020400;
RA   Bredin C.G., Sundqvist K.-G., Hauzenberger D., Klominek J.;
RT   "Integrin dependent migration of lung cancer cells to extracellular
RT   matrix components.";
RL   Eur. Respir. J. 11:400-407(1998).
//
RX   PubMed=12820372;
RA   Bergqvist M., Brattstrom D., Gullbo J., Hesselius P., Brodin O.,
RA   Wagenius G.;
RT   "p53 status and its in vitro relationship to radiosensitivity and
RT   chemosensitivity in lung cancer.";
RL   Anticancer Res. 23:1207-1212(2003).
//
RX   PubMed=21508355;
RA   Hedman M., Bergqvist M., Brattstrom D., Brodin O.;
RT   "Fractionated irradiation of five human lung cancer cell lines and
RT   prediction of survival according to a radiobiology model.";
RL   Anticancer Res. 31:1125-1130(2011).
//