ID   SGHPL-4
AC   CVCL_0521
SY   SGHPL4; CTB-CL-MC4; MC4; Saint Georges Hospital Placental cell Line-4
DR   BTO; BTO:0003980
DR   MCCL; MCC:0000419
DR   Lonza; 1281
DR   Wikidata; Q54953186
RX   PubMed=9804259;
RX   PubMed=10498850;
RX   PubMed=11723542;
RX   PubMed=19223288;
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
CC   Misspelling: SHGPL-4; Note=Once in text of PubMed 24103555.
CC   Derived from site: In situ; Placenta; UBERON=UBERON_0001987.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   <12FW
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 15
//
RX   PubMed=9804259; DOI=10.1093/humrep/13.10.2941;
RA   Choy M.Y., Manyonda I.T.;
RT   "The phagocytic activity of human first trimester extravillous
RT   trophoblast.";
RL   Hum. Reprod. 13:2941-2949(1998).
//
RX   PubMed=10498850; DOI=10.1038/sj.bjp.0702757; PMCID=PMC1571601;
RA   Cartwright J.E., Holden D.P., Whitley G.S.J.;
RT   "Hepatocyte growth factor regulates human trophoblast motility and
RT   invasion: a role for nitric oxide.";
RL   Br. J. Pharmacol. 128:181-189(1999).
//
RX   PubMed=11723542;
RA   Choy M.Y., Whitley G.S.J., Manyonda I.T.;
RT   "Efficient, rapid and reliable establishment of human trophoblast cell
RT   lines using poly-L-ornithine.";
RL   Early Pregnancy 4:124-143(2000).
//
RX   PubMed=19223288; DOI=10.1093/humrep/dep026;
RA   McCormick J., Whitley G.S.J., Le Bouteiller P., Cartwright J.E.;
RT   "Soluble HLA-G regulates motility and invasion of the
RT   trophoblast-derived cell line SGHPL-4.";
RL   Hum. Reprod. 24:1339-1345(2009).
//