Cellosaurus cell line (CVCL

Cellosaurus (CVCL_0429)

Comments

Senescence: It is possible that this cell line is not immortal and has a finite life span (personal communication of Kondo, Tadashi).
Doubling time: 64 hours (PubMed=32099531).

Sequence variations

Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=32099531).
Mutation; HGNC; HGNC:7765; NF1; Simple; p.Arg816Ter (c.2446C>T); ClinVar=VCV000280055; Zygosity=Heterozygous (PubMed=32099531).
Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu542Lys (c.1624G>A); ClinVar=VCV000031944; Zygosity=Unspecified (PubMed=32099531).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys135Trp (c.405C>G); ClinVar=VCV000376561; Zygosity=Heterozygous (PubMed=32099531).

Disease

Malignant peripheral nerve sheath tumor (NCIt: C3798)
Neurofibromatosis type 1 (NCIt: C3273)
Malignant peripheral nerve sheath tumor (ORDO: Orphanet_3148)
Neurofibromatosis type 1 (ORDO: Orphanet_636)

Species of origin

Mus musculus (Mouse) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_YU14 ! NCC-MPNST3-C1

Sex of cell

Male

Age at sampling

72Y