ID   MCF7/BUS
AC   CVCL_0413
SY   MCF-7/BUS; MCF-7 BUS; MCF7 BUS
DR   MCCL; MCC:0000309
DR   cancercelllines; CVCL_0413
DR   Millipore; SCC276
DR   Wikidata; Q54904465
RX   PubMed=7498097;
CC   Population: Caucasian.
CC   Characteristics: Shows a very high proliferative response to estradiol-17beta (PubMed=7498097).
CC   Doubling time: 32 +- 1.7 hours (Note=In 10% FBS-DME), 46 + 3.0 hours (Note=In CDHS-PhR DME) (PubMed=7498097).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): Millipore=SCC276
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 11
ST   D16S539: 11,12
ST   D18S51: 14
ST   D21S11: 30
ST   D3S1358: 16
ST   D5S818: 11,12
ST   D7S820: 8,9
ST   D8S1179: 10,14
ST   FGA: 23,24,25
ST   Penta D: 12
ST   Penta E: 7,12
ST   TH01: 6
ST   TPOX: 9,12
ST   vWA: 14,15
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 22
//
RX   PubMed=7498097; DOI=10.1289/ehp.95103844; PMCID=PMC1519213;
RA   Villalobos M., Olea N., Brotons J.A., Olea-Serrano M.F.,
RA   Ruiz de Almodovar J.M., Pedraza V.;
RT   "The E-screen assay: a comparison of different MCF7 cell stocks.";
RL   Environ. Health Perspect. 103:844-850(1995).
//