Cellosaurus INS-1E (CVCL_0351)
Cell line name | INS-1E |
---|---|
Synonyms | INS1-E; INS1E |
Accession | CVCL_0351 |
Resource Identification Initiative | To cite this cell line use: INS-1E (RRID:CVCL_0351) |
Comments | Characteristics: Used in numerous studies investigating the mechanisms of glucose stimulated insulin secretion. Is glucose responsive in a physiological range with substantial insulin content levels and a robust metabolism-secretion coupling (PubMed=30310992). Transformant: NCIt; C17262; X-Ray. Omics: Insulin secretory granules proteome analysis. Caution: This cell line is owned by the University of Geneva, Switzerland, who is the sole authorized distributor for both commercial and non-commercial research use. Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006. Cell type: Pancreatic beta cell; CL=CL_0000169. |
Disease | Rat insulinoma (NCIt: C121566) |
Species of origin | Rattus norvegicus (Rat)
(NCBI Taxonomy: 10116)
Breed/subspecies: NEDH; RS=RS:0000603. |
Hierarchy | Parent: CVCL_0352 (INS-1) |
Sex of cell | Male |
Age at sampling | 666D |
Category | Cancer cell line |
Web pages | https://www.unige.ch/unitec/files/9915/8470/0115/TechOffer739_INS-1E_cell_line.pdf |
Publications | PubMed=14592952; DOI=10.1210/en.2003-1099 PubMed=22569486; DOI=10.1016/j.jprot.2012.04.023 PubMed=30310992; DOI=10.1007/s00424-018-2215-z |
Cross-references | |
Cell line collections (Providers) | AddexBio; C0018009/4675 - Discontinued |
Cell line databases/resources | MCCL; MCC:0000245
Lonza; 1137 |
Anatomy/cell type resources | BCGO; BCGO_0000120
BTO; BTO_0003317 |
Chemistry resources | ChEMBL-Cells; CHEMBL4651375
PubChem_Cell_line; CVCL_0351 |
Encyclopedic resources | Wikidata; Q54897749 |
Proteomic databases | PRIDE; PXD006544
PRIDE; PXD008988 PRIDE; PXD011329 |
Entry history | |
Entry creation | 04-Apr-2012 |
Last entry update | 19-Dec-2024 |
Version number | 18 |