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Cellosaurus HL-60/VCR (CVCL_0305)

[Text version]
Cell line name HL-60/VCR
Synonyms HL60/VCR
Accession CVCL_0305
Resource Identification Initiative To cite this cell line use: HL-60/VCR (RRID:CVCL_0305)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_28445; Vincristine (VCR).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
Cross-references
Cell line databases/resources MCCL; MCC:0000197
cancercelllines; CVCL_0305
Encyclopedic resources Wikidata; Q54889809
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number23