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Cellosaurus HIB 1B (CVCL_0299)

[Text version]
Cell line name HIB 1B
Synonyms HIB-1B; HIB1B
Accession CVCL_0299
Resource Identification Initiative To cite this cell line use: HIB 1B (RRID:CVCL_0299)
Comments Characteristics: Expresses UCP. Differentiates into adipocyte-like cells (PubMed=1323843).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Brown adipose tissue; UBERON=UBERON_0001348.
Cell type: Preadipocyte; CL=CL_0002334.
Disease Mouse hibernoma (NCIt: C21634)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: aP2-TAg transgenic.
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Web pages Info; Wikipedia; -; https://ca.wikipedia.org/wiki/C%C3%A8l%C2%B7lules_HIB_1B
Publications

PubMed=1323843; DOI=10.1073/pnas.89.16.7561; PMCID=PMC49750
Ross S.R., Choy L., Graves R.A., Fox N., Solevjeva V., Klaus S., Ricquier D., Spiegelman B.M.
Hibernoma formation in transgenic mice and isolation of a brown adipocyte cell line expressing the uncoupling protein gene.
Proc. Natl. Acad. Sci. U.S.A. 89:7561-7565(1992)

PubMed=8175918; DOI=10.1242/jcs.107.1.313
Klaus S., Choy L., Champigny O., Cassard-Doulcier A.-M., Ross S.R., Spiegelman B.M., Ricquier D.
Characterization of the novel brown adipocyte cell line HIB 1B Adrenergic pathways involved in regulation of uncoupling protein gene expression.
J. Cell Sci. 107:313-319(1994)

Cross-references
Cell line databases/resources MCCL; MCC:0000190
Lonza; 279
Anatomy/cell type resources BTO; BTO_0005964
Encyclopedic resources Wikidata; Q54889533
Experimental variables resources EFO; EFO_0022808
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number13