ID   V79/E36-ts20
AC   CVCL_0215
SY   E36-ts20; E36ts20; TS20; ts20; ts 20
DR   MCCL; MCC:0000104
DR   Wikidata; Q54992616
RX   PubMed=3049611;
RX   PubMed=6752155;
CC   Characteristics: Has a thermolabile ubiquitin-like modifier-activating enzyme 1 (Uba1) (PubMed=3049611).
CC   Selected for resistance to: ChEBI; CHEBI:63486; 8-azaguanine.
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Misspelling: CHO-TS20; Note=Incorrect as not a CHO derivative but a V79 derivative.
CC   Misspelling: CHO-ts20; Note=Incorrect as not a CHO derivative but a V79 derivative.
CC   Misspelling: CHO ts20; Note=Incorrect as not a CHO derivative but a V79 derivative.
CC   Misspelling: CHOTS20; Note=Incorrect as not a CHO derivative but a V79 derivative.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_5A58 ! V79/E36
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 14
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RX   PubMed=3049611; DOI=10.1016/S0021-9258(19)37648-3;
RA   Kulka R.G., Raboy B., Schuster R., Parag H.A., Diamond G.,
RA   Ciechanover A., Marcus M.;
RT   "A Chinese hamster cell cycle mutant arrested at G2 phase has a
RT   temperature-sensitive ubiquitin-activating enzyme, E1.";
RL   J. Biol. Chem. 263:15726-15731(1988).
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RX   PubMed=6752155; DOI=10.1002/jcp.1041130125;
RA   Hirschberg J., Marcus M.;
RT   "Isolation by a replica-plating technique of Chinese hamster
RT   temperature-sensitive cell cycle mutants.";
RL   J. Cell. Physiol. 113:159-166(1982).
//