ID   CHL
AC   CVCL_0212
SY   Chinese Hamster Lung
DR   CLO; CLO_0002418
DR   CLO; CLO_0051575
DR   MCCL; MCC:0000101
DR   CLDB; cl720
DR   CCRID; 3101HAMGNHa2
DR   CCRID; 5301HAM-KCB08011YJ
DR   CLS; 305013
DR   ECACC; 87111906
DR   KCB; KCB 93014YJ
DR   KCB; KCB 200811YJ
DR   RCB; RCB0097
DR   Wikidata; Q54812127
RX   PubMed=688393;
RX   PubMed=1170023;
RX   PubMed=1370240;
RX   PubMed=3558490;
RX   PubMed=5452405;
RX   PubMed=7512690;
CC   Characteristics: Used in chemical substance-induced chromosomal aberration detection.
CC   Doubling time: ~30 hours (PubMed=5452405); ~14 hours (PubMed=1370240).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
SX   Female
AG   1D
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 20
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RX   PubMed=688393; DOI=10.1016/0092-8674(78)90354-9;
RA   Gupta R.S., Chan D.Y.-H., Siminovitch L.;
RT   "Evidence for functional hemizygosity at the Emtr locus in CHO cells
RT   through segregation analysis.";
RL   Cell 14:1007-1013(1978).
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RX   PubMed=1170023; DOI=10.1016/0092-8674(75)90021-5;
RA   Miyashita K., Kakunaga T.;
RT   "Isolation of heat- and cold-sensitive mutants of Chinese hamster lung
RT   cells affected in their ability to express the transformed state.";
RL   Cell 5:131-138(1975).
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RX   PubMed=1370240; DOI=10.1016/0027-5107(92)90036-2;
RA   Sawada M., Kitamura R., Kamataki T.;
RT   "Stable expression of monkey cytochrome P-450IA1 cDNA in Chinese
RT   hamster CHL cells and its application for detection of mutagenicity of
RT   aflatoxin B1.";
RL   Mutat. Res. 265:23-29(1992).
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RX   PubMed=3558490; DOI=10.1002/jcp.1041300303;
RA   Gupta R.S., Dudani A.K.;
RT   "Species-specific differences in the toxicity of rhodamine 123 towards
RT   cultured mammalian cells.";
RL   J. Cell. Physiol. 130:321-327(1987).
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RX   PubMed=5452405; DOI=10.20772/cancersci1959.61.2_161;
RA   Koyama H., Utakoji T., Ono T.;
RT   "A new cell line derived from newborn Chinese hamster lung tissue.";
RL   Gann 61:161-167(1970).
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RX   PubMed=7512690; DOI=10.1016/0165-7992(94)90033-7;
RA   Ono T., Norimatsu M., Yoshimura H.;
RT   "Induction of chromosome aberrations by pyrimethamine in cultured
RT   Chinese hamster (CHL) cells.";
RL   Mutat. Res. 323:197-201(1994).
//