ID   BV-2
AC   CVCL_0182
SY   BV2
DR   BTO; BTO:0003350
DR   EFO; EFO_0022792
DR   MCCL; MCC:0000073
DR   CLDB; cl7130
DR   BCRJ; 0356
DR   BioGRID_ORCS_Cell_line; 765
DR   CCRID; 1101MOU-PUMC000063
DR   CCRID; 4201MOU-CCTCC00311
DR   CCTCC; GDC0311
DR   ChEMBL-Cells; CHEMBL3307704
DR   ChEMBL-Targets; CHEMBL614781
DR   CLS; 305156
DR   GEO; GSM635468
DR   GEO; GSM635469
DR   GEO; GSM635470
DR   GEO; GSM635471
DR   ICLC; ATL03001
DR   KCB; KCB 200770YJ
DR   Lonza; 118
DR   PRIDE; PXD001597
DR   PRIDE; PXD004984
DR   PubChem_Cell_line; CVCL_0182
DR   Ubigene; YC-C035
DR   Wikidata; Q54798657
RX   DOI=10.1007/s13273-019-00057-6;
RX   PubMed=2110186;
RX   PubMed=19565166;
RX   PubMed=21214938;
RX   PubMed=21961028;
RX   PubMed=22651808;
RX   PubMed=26227174;
CC   Transformant: Recombinant retrovirus J2.
CC   Omics: Secretome proteome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
CC   Cell type: Microglial cell; CL=CL_0000129.
CC   Breed/subspecies: C57BL/6.
ST   Source(s): Ubigene=YC-C035
ST   Mouse STR 12-1: 16
ST   Mouse STR 15-3: 22.3,23.3,24.3
ST   Mouse STR 18-3: 16,17
ST   Mouse STR 4-2: 20.3
ST   Mouse STR 5-5: 17
ST   Mouse STR 6-4: 17.3
ST   Mouse STR 6-7: 15
ST   Mouse STR X-1: 27
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Female
AG   1W
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 27
//
RX   DOI=10.1007/s13273-019-00057-6;
RA   Mandal C., Yoon T., Park J.Y., Jung K.H., Chai Y.G.;
RT   "Lipopolysaccharide-dependent transcriptional regulation of PU.1 in
RT   microglial cells.";
RL   Mol. Cell. Toxicol. 16:51-61(2020).
//
RX   PubMed=2110186; DOI=10.1016/0165-5728(90)90073-V;
RA   Blasi E., Barluzzi R., Bocchini V., Mazzolla R., Bistoni F.;
RT   "Immortalization of murine microglial cells by a v-raf/v-myc carrying
RT   retrovirus.";
RL   J. Neuroimmunol. 27:229-237(1990).
//
RX   PubMed=19565166; DOI=10.14573/altex.2009.2.83;
RA   Henn A., Lund S., Hedtjarn M., Schrattenholz A., Porzgen P., Leist M.;
RT   "The suitability of BV2 cells as alternative model system for primary
RT   microglia cultures or for animal experiments examining brain
RT   inflammation.";
RL   ALTEX 26:83-94(2009).
//
RX   PubMed=21214938; DOI=10.1186/1471-2164-12-14; PMCID=PMC3024950;
RA   Atwood B.K., Lopez J., Wager-Miller J., Mackie K., Straiker A.;
RT   "Expression of G protein-coupled receptors and related proteins in
RT   HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray
RT   analysis.";
RL   BMC Genomics 12:14.1-14.14(2011).
//
RX   PubMed=21961028; DOI=10.2174/1877381801002010148; PMCID=PMC3180920;
RA   Crain J.M., Watters J.J.;
RT   "Estrogen and P2 purinergic receptor systems in microglia: therapeutic
RT   targets for neuroprotection.";
RL   Open Drug Discov. J. 2:148-167(2010).
//
RX   PubMed=22651808; DOI=10.1186/1742-2094-9-115; PMCID=PMC3407712;
RA   Stansley B., Post J., Hensley K.;
RT   "A comparative review of cell culture systems for the study of
RT   microglial biology in Alzheimer's disease.";
RL   J. Neuroinflammation 9:115.1-115.8(2012).
//
RX   PubMed=26227174; DOI=10.1002/pmic.201400623;
RA   Woo J.-M., Han D.-H., Park J.-H., Kim S.-J., Kim Y.-S.;
RT   "In-depth characterization of the secretome of mouse CNS cell lines by
RT   LC-MS/MS without prefractionation.";
RL   Proteomics 15:3617-3622(2015).
//