ID   Beta-TC-3
AC   CVCL_0172
SY   beta-TC-3; beta-TC3; beta TC3; BETA-TC-3; BETATC3; BetaTC3; betaTC3; bTC3
DR   BTO; BTO:0002993
DR   CLO; CLO_0001932
DR   MCCL; MCC:0000063
DR   ChEMBL-Cells; CHEMBL3308357
DR   ChEMBL-Targets; CHEMBL614063
DR   DSMZ; ACC-324
DR   DSMZCellDive; ACC-324
DR   IBRC; C10109
DR   PubChem_Cell_line; CVCL_0172
DR   TOKU-E; 4054
DR   Wikidata; Q54796097
RX   PubMed=1710218;
RX   PubMed=2848253;
RX   PubMed=22538498;
WW   https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/b/cell-lines-detail-210.html
CC   Doubling time: ~34 hours (DSMZ=ACC-324).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
CC   Cell type: Pancreatic beta cell; CL=CL_0000169.
CC   Breed/subspecies: (C57BL/6J x DBA/2J)F2 transgenic RIPTag2.
DI   NCIt; C34053; Mouse insulinoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 20
//
RX   PubMed=1710218; DOI=10.1016/S0021-9258(18)99139-8;
RA   Efrat S., Surana M., Fleischer N.;
RT   "Glucose induces insulin gene transcription in a murine pancreatic
RT   beta-cell line.";
RL   J. Biol. Chem. 266:11141-11143(1991).
//
RX   PubMed=2848253; DOI=10.1073/pnas.85.23.9037;
RA   Efrat S., Linde S., Kofod H., Spector D.L., Delannoy M., Grant S.G.N.,
RA   Hanahan D., Baekkeskov S.;
RT   "Beta-cell lines derived from transgenic mice expressing a hybrid
RT   insulin gene-oncogene.";
RL   Proc. Natl. Acad. Sci. U.S.A. 85:9037-9041(1988).
//
RX   PubMed=22538498; DOI=10.1159/000338793;
RA   Grozinsky-Glasberg S., Shimon I., Rubinfeld H.;
RT   "The role of cell lines in the study of neuroendocrine tumors.";
RL   Neuroendocrinology 96:173-187(2012).
//