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Cellosaurus AML12 (CVCL_0140)

[Text version]
Cell line name AML12
Synonyms AML-12; AML 12; Alpha Mouse Liver 12
Accession CVCL_0140
Resource Identification Initiative To cite this cell line use: AML12 (RRID:CVCL_0140)
Comments Doubling time: 37 hours (PubMed=7904757).
Genetic integration: Method=Transgenic mouse; Gene=HGNC; 11765; TGFA.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: CD-1 MT42 transgenic.
Hierarchy Children:
CVCL_D6AU (HyCyte AML12 KO-mIgf2)CVCL_E1J5 (HyCyte AML12 KO-mNsun6)CVCL_D8DT (Ubigene AML12 Atp7b KO)
CVCL_D8DU (Ubigene AML12 Cs KO)CVCL_D8DV (Ubigene AML12 Faah KO)CVCL_D8DW (Ubigene AML12 Fasn KO)
CVCL_D8DX (Ubigene AML12 Ldlr KO)
Sex of cell Male
Age at sampling 5M
Category Spontaneously immortalized cell line
STR profile Source(s): Ubigene=YC-D022

Markers:
Mouse STR 4-220.3
Mouse STR 5-514,15
Mouse STR 6-416
Mouse STR 6-712
Mouse STR 12-119
Mouse STR 15-321.3
Mouse STR 18-321
Mouse STR X-126

Run an STR similarity search on this cell line
Web pages https://www.atcc.org/en/support/technical-support/faqs/morphology-of-atcc-crl-2254
Publications

PubMed=7904757; DOI=10.1073/pnas.91.2.674; PMCID=PMC43011
Wu J.C., Merlino G.T., Fausto N.
Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha.
Proc. Natl. Acad. Sci. U.S.A. 91:674-678(1994)

Cross-references
Cell line collections (Providers) ATCC; CRL-2254
BCRC; 60326
BCRJ; 0354
CLS; 300643
IZSLER; BS CL 161
Ubigene; YC-D022
Cell line databases/resources CLO; CLO_0001716
MCCL; MCC:0000033
CCRID; 3101MOUSCSP550
Anatomy/cell type resources BTO; BTO:0003449
Encyclopedic resources Wikidata; Q54749800
Gene expression databases GEO; GSE87156
GEO; GSM294842
GEO; GSM296415
GEO; GSM296416
GEO; GSM296417
GEO; GSM1374079
GEO; GSM1374080
GEO; GSM1374081
GEO; GSM1374082
GEO; GSM1374083
GEO; GSM1374084
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number20