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Cellosaurus SNU-638 (CVCL_0102)

[Text version]
Cell line name SNU-638
Synonyms SNU638
Accession CVCL_0102
Resource Identification Initiative To cite this cell line use: SNU-638 (RRID:CVCL_0102)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 25 hours (PubMed=29435981).
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 7029; MET; Simple; p.Asn375Ser (c.1124A>G); ClinVar=VCV000041611; Zygosity=Unspecified (PubMed=29435981).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Heterozygous (PubMed=9033653).
HLA typing Source: PubMed=25960936
Class I
HLA-AA*03:19,24:02
HLA-BB*44:02,52:01
HLA-CC*05:01,12:02
Class II
HLA-DQDQB1*06:02,06:02
HLA-DRDRB1*15:01,15:01

Source: PubMed=26589293
Class I
HLA-AA*03:19,24:02
HLA-BB*44:02,52:01
HLA-CC*05:01,12:02
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C9BY (638-F1)CVCL_C9BZ (638-F2)CVCL_L047 (SNU-638-5FU)
CVCL_L048 (SNU-638-CIS)
Sex of cell Male
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001664; KCLB=00638; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,12
D3S135815
D5S81810,13,14,15 (PubMed=25877200)
10,13,14,15,16 (DepMap=ACH-001664)
10,14 (KCLB=00638)
D7S8209,10
D8S117911,13
D13S31710
D16S53911,13 (KCLB=00638; PubMed=25877200)
11,13,14 (DepMap=ACH-001664)
D18S5114,16
D21S1130.2,31
FGA17,26,27 (DepMap=ACH-001664)
17,27 (PubMed=25877200)
Penta D9
Penta E14,18
TH017
TPOX8,11
vWA14,19

Run an STR similarity search on this cell line
Publications

PubMed=9033653; DOI=10.1002/(SICI)1097-0215(19970207)70:4<443::AID-IJC12>3.0.CO;2-G
Park J.-G., Yang H.-K., Kim W.-H., Chung J.-K., Kang M.-S., Lee J.-H., Oh J.H., Park H.-S., Yeo K.-S., Kang S.H., Song S.-Y., Kang Y.K., Bang Y.-J., Kim Y.I., Kim J.-P.
Establishment and characterization of human gastric carcinoma cell lines.
Int. J. Cancer 70:443-449(1997)

PubMed=10812166; DOI=10.1016/S0165-4608(99)00217-4
Chun Y.-H., Kil J.-I., Suh Y.-S., Kim S.-H., Kim H., Park S.-H.
Characterization of chromosomal aberrations in human gastric carcinoma cell lines using chromosome painting.
Cancer Genet. Cytogenet. 119:18-25(2000)

PubMed=10974411; DOI=10.1016/S0304-3835(00)00535-8
Chung Y.M., Park S.-H., Park J.K., Kim Y.-T., Kang Y.-K., Yoo Y.D.
Establishment and characterization of 5-fluorouracil-resistant gastric cancer cells.
Cancer Lett. 159:95-101(2000)

PubMed=15723654; DOI=10.1111/j.1349-7006.2005.00016.x; PMCID=PMC11160020
Takada H., Imoto I., Tsuda H., Sonoda I., Ichikura T., Mochizuki H., Okanoue T., Inazawa J.
Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization.
Cancer Sci. 96:100-110(2005)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1; PMCID=PMC2785416
Ku J.-L., Park J.-G.
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

PubMed=24807215; DOI=10.1038/ncomms4830; PMCID=PMC4024760
Liu J.-F., McCleland M.L., Stawiski E.W., Gnad F., Mayba O., Haverty P.M., Durinck S., Chen Y.-J., Klijn C., Jhunjhunwala S., Lawrence M., Liu H.-B., Wan Y.-N., Chopra V.S., Yaylaoglu M.B., Yuan W.-L., Ha C., Gilbert H.N., Reeder J., Pau G., Stinson J., Stern H.M., Manning G., Wu T.D., Neve R.M., de Sauvage F.J., Modrusan Z., Seshagiri S., Firestein R., Zhang Z.-M.
Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
Nat. Commun. 5:3830.1-3830.8(2014)

PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=29435981; DOI=10.1002/ijc.31304
Kim H.J., Kang S.K., Kwon W.S., Kim T.S., Jeong I., Jeung H.-C., Kragh M., Horak I.D., Chung H.C., Rha S.Y.
Forty-nine gastric cancer cell lines with integrative genomic profiling for development of c-MET inhibitor.
Int. J. Cancer 143:151-159(2018)

Cross-references
Cell line collections (Providers) KCLB; 00638
Cell line databases/resources cancercelllines; CVCL_0102
Cell_Model_Passport; SIDM01769
CGH-DB; 127-1
CGH-DB; 9015-4
DepMap; ACH-001664
Anatomy/cell type resources BTO; BTO:0003478
Biological sample resources BioSample; SAMN03473180
Chemistry resources ChEMBL-Cells; CHEMBL3307747
ChEMBL-Targets; CHEMBL614935
PharmacoDB; SNU638_1476_2019
PubChem_Cell_line; CVCL_0102
Encyclopedic resources Wikidata; Q54955236
Experimental variables resources EFO; EFO_0006758
Gene expression databases ArrayExpress; E-MTAB-2706
GEO; GSM1374896
Polymorphism and mutation databases Cosmic; 685583
Cosmic; 848143
Cosmic; 869511
Cosmic; 921601
Cosmic; 1067207
Cosmic; 1090457
Cosmic; 1294961
Cosmic; 1528878
Cosmic; 2036662
Cosmic; 2373753
Cosmic; 2484959
Cosmic; 2646587
Cosmic; 2807650
IARC_TP53; 7421
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number35