Cellosaurus cell line SD-1 (CVCL

Cellosaurus SD-1 (CVCL_0094)

[Text version]

Cell line name

SD-1

Synonyms

SD1

Accession

CVCL_0094

Resource Identification Initiative

To cite this cell line use: SD-1 (RRID:CVCL_0094)

Comments

Doubling time: ~28-32 hours (DSMZ=ACC-366).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.

Sequence variations

Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 1 fused to ABL1 exon 2 (e1a2 transcript) (PubMed=10071072; PubMed=10576511; PubMed=15843827).

Disease

Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C114819)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

Adult

Category

Transformed cell line

STR profile

Source(s): AddexBio=C0003015/4882; DSMZ=ACC-366

Markers:

Amelogenin	X
CSF1PO	11
D2S1338	19,20
D3S1358	16,18
D5S818	11
D7S820	9
D8S1179	14,16
D13S317	12
D16S539	9,11
D18S51	12,13
D19S433	13,14
D21S11	28,32
FGA	20,26
Penta D	9,12
Penta E	5,13
TH01	6,7
TPOX	8,11
vWA	14,16

Publications

PubMed=1847983
Dhut S., Gibbons B., Chaplin T., Young B.D.
Establishment of a lymphoblastoid cell line, SD-1, expressing the p190 bcr-abl chimaeric protein.
Leukemia 5:49-55(1991)

PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9
Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.
ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.
Leuk. Res. 23:1055-1060(1999)

PubMed=15843827; DOI=10.1038/sj.leu.2403749
Andersson A., Eden P., Lindgren D., Nilsson J., Lassen C., Heldrup J., Fontes M., Borg A., Mitelman F., Johansson B., Hoglund M., Fioretos T.
Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations.
Leukemia 19:1042-1050(2005)

PubMed=20454443; DOI=10.1155/2010/904767; PMCID=PMC2861168
Uphoff C.C., Denkmann S.A., Steube K.G., Drexler H.G.
Detection of EBV, HBV, HCV, HIV-1, HTLV-I and -II, and SMRV in human and other primate cell lines.
J. Biomed. Biotechnol. 2010:904767.1-904767.23(2010)

Cross-references

Cell line collections (Providers)

AddexBio; C0003015/4882 - Discontinued
DSMZ; ACC-366

Cell line databases/resources

CLO; CLO_0008975
DSMZCellDive; ACC-366

Biological sample resources

BioSample; SAMN03473320

Encyclopedic resources

Wikidata; Q54952709

Gene expression databases

GEO; GSM236804
GEO; GSM236840

Polymorphism and mutation databases

Cosmic; 1019835
Cosmic; 1026576
Cosmic; 1498419
Cosmic; 1524819

Entry history

Entry creation

04-Apr-2012

Last entry update

19-Dec-2024

Version number