ID   BEL-1
AC   CVCL_0081
SY   BEL1
DR   Cosmic; 2542842
DR   DSMZ; ACC-968
DR   Wikidata; Q54795965
RX   PubMed=14671638;
RX   PubMed=15327532;
CC   Doubling time: 38 +- 2 hours (PubMed=15327532); ~48 hours (DSMZ=ACC-968).
CC   Sequence variation: Gene fusion; HGNC; HGNC:7135; AFF1 + HGNC; HGNC:7132; KMT2A; Name(s)=KMT2A-AFF1, MLL-AFF1, ALL-1/AF4 (PubMed=14671638).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
ST   Source(s): DSMZ=ACC-968
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 8,11
ST   D16S539: 11,12
ST   D18S51: 12,13
ST   D19S433: 12,15
ST   D21S11: 28,29
ST   D2S1338: 18,20
ST   D3S1358: 15
ST   D5S818: 10,12
ST   D7S820: 9,10
ST   D8S1179: 14
ST   FGA: 20,21
ST   Penta D: 13
ST   Penta E: 7,11
ST   TH01: 6
ST   TPOX: 9,11
ST   vWA: 17
DI   NCIt; C9143; Adult B acute lymphoblastic leukemia
DI   NCIt; C80342; B acute lymphoblastic leukemia with t(v;11q23.3) MLL rearranged
DI   ORDO; Orphanet_585918; B-lymphoblastic leukemia/lymphoma with t(v;11q23.3)
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   41Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 23
//
RX   PubMed=14671638; DOI=10.1038/sj.leu.2403236;
RA   Drexler H.G., Quentmeier H., MacLeod R.A.F.;
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   MLL gene alterations.";
RL   Leukemia 18:227-232(2004).
//
RX   PubMed=15327532; DOI=10.1111/j.1365-2141.2004.05122.x;
RA   Tang R.-P., Faussat A.-M., Perrot J.-Y., Dubrulle S., Ramond S.,
RA   Delmer A., Ajchenbaum-Cymbalista F., Marie J.-P.;
RT   "A new acute lymphoblastic leukaemia cell line BEL-1 with t(4; 11)
RT   (q21; q23) chromosomal translocation and a unique aberrant p27
RT   transcript.";
RL   Br. J. Haematol. 126:754-755(2004).
//