Cellosaurus logo
expasy logo

Cellosaurus U-266/84 (CVCL_0016)

[Text version]
Cell line name U-266/84
Accession CVCL_0016
Resource Identification Initiative To cite this cell line use: U-266/84 (RRID:CVCL_0016)
Comments Population: Caucasian.
Characteristics: Produces IgE lambda (from parent cell line).
Omics: Deep antibody staining analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Lys601Asn (c.1803A>T); ClinVar=VCV000376285; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7329; MSH6; Simple; p.Gly141Asp (c.422G>A); ClinVar=VCV001491786; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 12033; TRAF3; Simple; p.Lys550Leufs*3 (c.1648_1649insT); Zygosity=Homozygous (from parent cell line).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0566 (U266B1)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Web pages https://www.proteinatlas.org/learn/cellines
Publications

PubMed=3133230; DOI=10.1002/eji.1830180611
Hellman L., Josephson S., Jernberg-Wiklund H., Nilsson K., Pettersson U.
Immunoglobulin synthesis in the human myeloma cell line U-266 expression of two immunoglobulin heavy chain isotypes (epsilon and alpha) after long-term cultivation in vitro.
Eur. J. Immunol. 18:905-910(1988)

Cross-references
Cell line databases/resources cancercelllines; CVCL_0016
Encyclopedic resources Wikidata; Q54973558
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number22