Cellosaurus cell line U-266/70 (CVCL

Cross-references
Cell line name	U-266/70
Accession	CVCL_0015
Resource Identification Initiative	To cite this cell line use: U-266/70 (RRID:CVCL_0015)
Comments	Population: Caucasian. Characteristics: Produces IgE lambda (from parent cell line). Omics: Deep antibody staining analysis. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: B-cell; CL=CL_0000236.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Lys601Asn (c.1803A>T); ClinVar=VCV000376285; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Gly141Asp (c.422G>A); ClinVar=VCV001491786; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ala161Thr (c.481G>A); ClinVar=VCV000161518; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:12033; TRAF3; Simple; p.Lys550Leufs*3 (c.1648_1649insT); Zygosity=Homozygous (from parent cell line).
Disease	Plasma cell myeloma (NCIt: C3242) Multiple myeloma (ORDO: Orphanet_29073)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0566 (U266B1)
Sex of cell	Male
Age at sampling	53Y
Category	Cancer cell line
Web pages	https://www.proteinatlas.org/learn/cellines
Cell line databases/resources	cancercelllines; CVCL_0015
Encyclopedic resources	Wikidata; Q54973557
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	23