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Cellosaurus RK3E-ras (CVCL_C5TP)

[Text version]
Cell line name RK3E-ras
Synonyms RK3E-RAS
Accession CVCL_C5TP
Resource Identification Initiative To cite this cell line use: RK3E-ras (RRID:CVCL_C5TP)
Comments Characteristics: Tumorigenic.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: Adenovirus E1A.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS:0000215.
Hierarchy Parent: CVCL_0503 (RK3E)
Sex of cell Sex unspecified
Age at sampling 7D
Category Transformed cell line
Publications

PubMed=1825351; DOI=10.1128/mcb.11.3.1724-1728.1991; PMCID=PMC369482
Ruppert J.M., Vogelstein B., Kinzler K.W.
The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A.
Mol. Cell. Biol. 11:1724-1728(1991)

Cross-references
Encyclopedic resources Wikidata; Q116050177
Entry history
Entry creation15-Dec-2022
Last entry update10-Sep-2024
Version number5