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Cellosaurus PPMI.I.1022.3 (CVCL_D5N8)

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Cell line name PPMI.I.1022.3
Synonyms PPMI3446; PPMI_3446; CDIi017-A; FCDI_11296
Accession CVCL_D5N8
Resource Identification Initiative To cite this cell line use: PPMI.I.1022.3 (RRID:CVCL_D5N8)
Comments Part of: Parkinson's Progression Marker Initiative (PPMI) cell line panel.
Population: Caucasian, not Hispanic.
Omics: Genome sequenced.
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: PPMI study cohort PD, PPMI study subgroup sporadic.
Caution: The PPMI3446 and PPMI_3446 identifiers correspond to an internal donor ID at PPMI. As multiple iPSC clones have been established from the cells of this donor, these identifiers should not be cited in a publication. Note that FujiFilm Cellular Dynamics, Inc (FCDI) and hPSCreg have assigned only a single identifier for all of the PBMC derived clones.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Parkinson's disease (NCIt: C26845)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D5N6 ! PPMI.I.1022.1
CVCL_D5N7 ! PPMI.I.1022.2
CVCL_D5N9 ! PPMI.I.1022.4
CVCL_D5NA ! PPMI.I.1022.5
CVCL_D5NB ! PPMI.I.1022.6
Sex of cell Male
Age at sampling 75-79Y
Category Induced pluripotent stem cell
Web pages https://www.ppmi-info.org/access-data-specimens/download-data
https://www.michaeljfox.org/sites/default/files/media/document/2018%20-%20PDTC%20-%20NKP%20Poster%20on%20iPSCs.pdf
Publications

PubMed=35895835; DOI=10.1126/scitranslmed.abp8869
Langston R.G., Beilina A., Reed X., Kaganovich A., Singleton A.B., Blauwendraat C., Gibbs J.R., Cookson M.R.
Association of a common genetic variant with Parkinson's disease is mediated by microglia.
Sci. Transl. Med. 14:eabp8869.1-eabp8869.12(2022)

PubMed=36950378; DOI=10.1016/j.xgen.2023.100261
Bressan E., Reed X., Bansal V., Hutchins E., Cobb M.M., Webb M.G., Alsop E., Grenn F.P., Illarionova A., Savytska N., Violich I., Broeer S., Fernandes N., Sivakumar R., Beilina A., Billingsley K.J., Berghausen J., Pantazis C.B., Pitz V., Patel D., Daida K., Meechoovet B., Reiman R., Courtright-Lim A., Logemann A., Antone J., Barch M., Kitchen R., Li Y., Dalgard C.L., Rizzu P., Hernandez D.G., Hjelm B.E., Nalls M.A., Gibbs J.R., Finkbeiner S., Cookson M.R., Van Keuren-Jensen K., Craig D.W., Singleton A.B., Heutink P., Blauwendraat C.
The Foundational Data Initiative for Parkinson Disease: enabling efficient translation from genetic maps to mechanism.
Cell Genom 3:100261.1-100261.25(2023)

Cross-references
Cell line databases/resources hPSCreg; CDIi017-A
Biological sample resources BioSamples; SAMEA115473768
Entry history
Entry creation02-May-2024
Last entry update02-May-2024
Version number1