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Cellosaurus 143B pML BK TK (CVCL_3477)

[Text version]
Cell line name 143B pML BK TK
Synonyms 143B PML BK TK
Accession CVCL_3477
Resource Identification Initiative To cite this cell line use: 143B pML BK TK (RRID:CVCL_3477)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8304.
Population: Caucasian.
Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Ala59Thr (c.175G>A); ClinVar=VCV000012581; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2270 (143B)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-8304

Markers:
AmelogeninX
CSF1PO12
D2S133824,25
D3S135815
D5S81813
D7S82011,12
D8S117911,14
D13S31712
D16S53910,13
D18S5117
D19S43313
D21S1131.2,32.2
FGA24
Penta D9,10
Penta E7,12
TH016
TPOX11
vWA18

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Publications

Patent=US4562155
Ricciardi R.P., Barbanti-Brodano G., Milanesi G.
Hybrid viral plasmid and microorganisms containing same.
Patent number US4562155, 31-Dec-1985

Cross-references
Cell line collections (Providers) ATCC; CRL-8304
Cell line databases/resources CLO; CLO_0001089
cancercelllines; CVCL_3477
LINCS_LDP; LCL-1418
Encyclopedic resources Wikidata; Q54581908
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number24